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By targeting key cellular mechanisms, including oxidative stress, calcium influx, and membrane phospholipid asymmetry, these agents offer potential therapeutic uses for disorders associated with excessive erythrocyte death, such as hemolytic anemias, CKD, and metabolic syndromes
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The concept of neuroprotective (A2-type) and neurotoxic (A1-type) reactive astrocytes reflects dynamic transitional states within a continuum of the same astrocyte lineage, rather than fixed subtypes
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