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10 Unlike traditional antidepressants that take weeks to alter mood, esketamine demonstrates that modulating the NMDAR can produce rapid, sustained antidepressant effects within hours in patients who have failed multiple previous therapies with selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs)

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L-Theanine preserves skin histological architecture Hematoxylin and eosin staining revealed pronounced epidermal thinning and inflammatory cell infiltration in the model group