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When the body is unable to produce as many healthy red blood cells as it needs, which is often the case with a vitamin B12 deficiency, it leads to a condition called anemia ( Anemia makes you feel weak and fatigued
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There is a similar beneficial effect in the rats with the Pringle maneuver, ischemia, reperfusion, and suprahepatic inferior caval vein occlusion (Budd–Chiari syndrome) (Kolovrat et al., 2020)
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