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The GluN2C subunit is enriched in the cerebellar granule cells, but knockout of GluN2C subunits does not result in any motor deficits 6,7 , consistent with suggestions that GluN2C is redundant with GluN2A in cerebellar function
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Left panel : summarizes the pharmacology and mechanisms of action of kratom’s principal indole alkaloids, mitragynine and 7-hydroxymitragynine, which mediate many of the plant’s biological effects
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