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Given that reactive astrocytes can adopt either neurotoxic or neuroprotective phenotypes, both profiles present opportunities for interventions
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The microbial PhIP metabolite 7-hydroxy-5-methyl-3-phenyl-6,7,8,9-tetrahydropyrido[3′,2′:4, 5]imidazo[1,2-a]pyrimidin-5-ium chloride (PhIP-M1) induces DNA damage, apoptosis and cell cycle arrest towards Caco-2 cells
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