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Studies in human hepatoma cells have shown that GSTP1 is able to bind to signal transduction and transcriptional activator 3 (STAT3) to form the GSTP1-STAT3 complex, inhibiting epidermal growth factor (EGF)-mediated phosphorylation of STAT3 tyrosine and preventing its transcriptional activity, thereby reducing cell proliferation and halting the cell cycle [73]
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Intoxikationen, die im menschlichen Organismus über radikalische Kettenreaktionen zu Biomolekül- und Gewebeschäden führen.Intoxications that lead to biomolecule and tissue damage in the human organism via radical chain reactions
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