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Acknowledgements This work was financed by the University of Lodz under the “Excellence Initiative - Research University” program

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the heterologous nucleic acid such as DNA the heterologous nucleic acid can in some manner mediate expression of DNA that encodes the therapeutic product, or it can encode a product, such as a peptide or RNA that in some manner mediates, directly or indirectly, expression of a therapeutic product Genetic therapy can also be used to deliver nucleic acid encoding a gene product that replaces a defective gene or supplements a gene product produced by the mammal or the cell in which it is introduced