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As potent forms of environmental stimuli, drugs of abuse affect the expression and activity of DNA epigenetic machinery (Figure 1

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Methylglyoxal Detoxication: Lessons from a Cyanobacterium Little attention has been paid to MG production, signaling and detoxification systems in photosynthetic organisms, although they produce MG by the catabolism of sugars, amino acids and lipids, such as heterotrophic organisms, but also by their active assimilation of CO 2 driven by photosynthesis [54,232,243]