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At high concentrations, BAC solubilizes hydrophobic membrane components by forming micellar aggregates.3 The antibacterial activity of BAC may also involve the disruption and denaturation of structural membrane proteins.17 The outer membrane of Gram-negative bacterial cells constitutes a semi-permeable barrier that prevents many otherwise effective antibacterial agents from reaching their molecular targets in bacteria.5,6 The action of QACs on bacterial cells alters the permeability of the outer membrane and thus affects their antibiotic susceptibility