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Novel pharmacologic approaches, including low-dose naltrexone, act by attenuating microglial activation and neuroinflammatory cascades, offering potential therapeutic avenues for patients with heightened central immune signaling [170]
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Later studies revealed that just like proteins, carbohydrates and nucleic acids, lipids are targets of various reactive oxygen and nitrogen species and oxidized to give a diverse array of products.38 Studies have revealed that lipid peroxidation severely affects biomembranes
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