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Hankey 6 , Cat Graham 7 1 University of Edinburgh, Usher Institute, Edinburgh, United Kingdom , 2 Uppsala University, Department of Medical Sciences, Neurology, Uppsala, Sweden , 3 George Institute, Mental Health Program, Sydney, Australia , 4 The University of Central Lancashire, Faculty of Health and Care, Preston, United Kingdom , 5 University of Edinburgh, Centre for Clinical Brain Sciences, Edinburgh, United Kingdom , 6 University of Western Australia, Faculty of Health and Medical Sciences, Perth, Australia , 7 University of Edinburgh, Welcome Trust Clinical Research Facility, Edinburgh, United Kingdom Background and aims: Three large randomized trials of fluoxetine for stroke recovery (FOCUS (fluoxetine or control under supervision), AFFINITY (the Assessment oF FluoxetINe In sTroke recovery) and EFFECTS (Efficacy oF Fluoxetine-a randomisEd Controlled Trial in Stroke)) were collaboratively designed (same core protocol) to facilitate an individual patient data meta-analysis

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