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As RANKL expression was decreased in the periligative gingival tissues of aly/aly mice, LPS-induced RANKL expression in POB from aly/aly mice may suppress compared with POB from WT mice
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In summary, luteolin has the potential to alleviate inflammation and oxidative stress and improve cilia function in COPD by inhibiting NOX4-mediated NF-κB signaling pathway, regulating TRPV1 and CYP2A13/NRF2 signaling pathways, and modulating various signaling pathways and cytokines
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