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The small or missing regions of the anterior commissure of Tbr1 +/– mice lead to defective neuronal differentiation in the amygdala, which may serve as a suitable model for determining how autism genes control neuronal circuits, neural activity, and behaviors (Huang et al., Cntn4 KO mice model showed increased stress responses, decreased synaptic potentiation, and abnormal dendritic arborization and spines of hippocampal CA1 neurons (Oguro-Ando et al., 2021)
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79 Sulpiride is an antidepressant that blocks the ability of the GLT-1 inhibitor TFB-TBOA to induce synaptic depression 80 and partly attenuates the impact of fluorocitrate (a metabolic uncoupler that blocks aconitase in the tricarboxylic acid (TCA) cycle) on synaptic output
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