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Thus, in this study, we examined the bioactivity of crude HEM and its three bioactive compounds (HeA, HeC, and HeS) in stimulating OPC differentiation into mature OLs with the expression of myelin proteins, MBP and myelin proteolipid protein (PLP)
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Mipomersen The drug mipomersen (Kynamro®) is an anti-sense oligonucleotide (ASO) that targets the apoB mRNA in the liver, thereby resulting in reduced synthesis of the apoB-100 protein
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