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Whether the isolated fragment can recapitulate that presentation is exactly the question, and the structural argument cuts both ways: it explains why a fragment might behave differently from the parent, and it also explains why a fragment might fail to behave like the parent at all

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A 2013 safety analysis by Stier and colleagues pooled data from six trials covering 893 participants and reported a good safety and side-effect profile, with the compound acting on fat metabolism through a lipolytic route and no appetite-suppressant action