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In a controlled clinical comparison against phenazepam, a potent benzodiazepine widely prescribed in Russia, Selank achieved comparable anxiety reduction without any of the sedation, muscle relaxation, or withdrawal syndrome observed with the benzodiazepine comparator

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Aside from cytosolic amino acid sensors, intra-lysosomal amino acid sensing coincided with the identification of SLC38A9, a lysosomal transmembrane protein likely belonging to arginine transporters and an integral part of mTORC1 activation via Ragulator-RAG GTPases (Jung et al., 2015