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Role of hepatic stellate cell (HSC)-derived cytokines in hepatic inflammation and immunity
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When IGF-IR is deleted in mature osteoblasts, using OCN promoter-driven Cre line, the KO mice produce less trabecular bone, with an increased proportion of osteoid in the bone, indicating impaired mineralizing functions in OCN IGF-IR −/− osteoblasts (58,59)
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