igf-1 lr3 receptor grade LR3-IGF-I (Receptor Grade), Human mTOR-dependent dysregulation of autophagy

mTOR-dependent dysregulation of autophagy contributes to the retinal ganglion cell loss in streptozotocin-induced diabetic retinopathy | Cell Communication and Signaling | Springer Nature Link

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Inhibition of SMG1 and DNA-PK disrupts redox homeostasis, resulting in increased ROS levels and ferrous iron accumulation, lipid hydroperoxide generation, reduced cell viability, and enhanced ferroptotic vulnerability in cancer cells and mouse liver