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Weijie Xu, [email protected] †These authors have contributed equally to this work ‡ORCID: Zongxin Ling, orcid.org/0000-0001-9662-099X This article was submitted to Intestinal Microbiome, a section of the journal Frontiers in Cellular and Infection Microbiology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers