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A compound that is clean enough for a binding assay is not automatically clean enough for a quantitative cell-based readout where a co-eluting impurity could carry activity of its own

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By modulating autoimmune responses, enhancing antigen presentation, and disrupting inhibitory tumor microenvironment (TME), this groundbreaking approach strengthens the immune system’s ability to detect and eliminate cancer cells (Mehta et al., 2017)