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Third, although we have previously reported that elevation of HO-1 induced lethal fibrosis in acute exacerbation of IPF triggered by COVID-19, it is necessary to perform a molecular pathological study regarding the in vivo dynamics of serum HO-1 elevation and pro-fibrotic cytokines such as tissue growth factor-β1 43
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Several groups have encapsulated enzymes, antibodies, and other proteins within silica composites to address stability issues in the design of biosensors, biocatalysts, and bioreactors
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