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In these antioxidant reactions, glutathione is oxidized to form the oxidized disulfide form, GSSG — which is then, in turn, reduced back to glutathione using NADPH.[ref] Mitochondria are essential for the production of ATP for energy storage in cells

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Second, some molecular regulators exhibit seemingly contradictory pro-tumor functions despite their ability to induce a tumor-suppressive form of death such as ferroptosis