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In a 2012 study published in the International Journal of Physiology, Pathophysiology and Pharmacology , KPV was found to suppress NF-κB, which is known to induce the expression of inflammatory genes and regulate the survival, activation, and differentiation of inflammatory T cells.8 9 Having this suppressive property, KPV could be a potential treatment for serious inflammatory health conditions affecting the lungs or gastrointestinal tract, in which the NF-κB pathway plays a key role.8 10 Indeed, a 2017 study in a mouse model observed that KPV administration led to significant downregulation of TNF-α, a major cytokine encoded by the pro-inflammatory TNFA gene and which uses the NF-κB pathway.11 12 As an antimicrobial In 2000, the Journal of Leukocyte Biology published an in vitro study describing the effect that KPV (and α-MSH more broadly) could have on common pathogens

Health Concern: Weight Management

Size:360 Tablets

Michael Genovese, M.D., is a board-certified physician and the Chief Medical Advisor at Ascendant New York