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Additionally, it suppresses the expression of PGC-1α and its downstream gluconeogenic enzymes, PEPCK and G6Pase, thereby decreasing hepatic glucose production (HGP) through the inactivation of CREB via dephosphorylation [46]
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Prior experiments demonstrated that the TMEM41B encoded protein functions in intracellular lipid transport and in the assembly of autophagosomes
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