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Therefore, mitochondrial malfunction and the formation of ROS, toxic to motor neurons in amyotrophic lateral sclerosis (ALS), are strongly associated with mutations in key genes, including SOD1 [193]
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10.1001/jama.2008.864 10.1001/jama.2008.864 [DOI] [PMC free article] [PubMed] [Google Scholar] Litchfield MH (2005) Estimates of acute pesticide poisoning in agriculturalworkers in less developed countries
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