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Oral peak plasma concentration: approximately 2,252 ng/mL Absolute oral bioavailability: 38.4% Oral terminal half-life: approximately 6.9 hours Intravenous terminal half-life: approximately 3.8 hours Intravenous bioavailability: 100% by definition as the reference route The longer terminal half-life after oral administration can reflect absorption continuing while elimination is occurring—a phenomenon sometimes described as absorption-limited or “flip-flop” kinetics
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