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[DOI] [PMC free article] [PubMed] [Google Scholar] 21.Yasaka T, Okudaira K, Fujito H, Matsumoto J, Ohya I, Miyamoto Y

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23 These symptoms can be severe in some patients, resulting in a pause of dose escalation, and if intolerable GI symptoms continue, a dose adjustment to the previous lower dose or a switch to an alternative GLP-1 RA should be considered