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The study found that cefiderocol was able to achieve microbiological eradication in 53% of patients with UTI, while only 20% of patients in the BAT group with UTI were able to achieve the same result ( E
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Additionally, mtDNA in vascular cells activates the NOD-like receptor protein 3 (NLRP3) inflammasome, leading to the activation of pro-inflammatory cytokines IL-18 and IL-1β [146, 147]
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