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Currently, the pan-FGFR inhibitor Erdafitinib is approved for the treatment of adults with locally advanced or metastatic urothelial carcinoma harbouring FGFR2 or FGFR3 alterations who have progressed following chemotherapy 9
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For example, tolbutamide (Figure 18) is an anti-diabetic drug and it has a shorter half-life (2.5 hrs)
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