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in Trends in Neurosciences (1980) characterized DSIP’s role as a neuromodulator and established its central physiological effects
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Most likely, such an inhibition involved chemical crosslinking of Tau by reaction of the oleocanthal dialdehydic group with lysine residues, thus arresting the conversion of Tau from random coil to β-sheet and promoting an increase of α-helical structure [307]
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