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If the question matters to your work, the comparison has to be made in a human-derived system rather than inferred from rodent data

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In the 1920’s world of clinical neurology, momentum gathered behind the idea of treating epileptic seizures not with the few and rather inadequate medications available at the time, but by a radical change in diet: elimination of all but a tiny amount of ingested carbohydrate and substitution mostly by dietary fat, a so-called “ketogenic diet” (Box 1)